The novel Cleavage High-throughput Assay (CHiTA) developed at Penn State provides a scarless method to characterize thousands of diverse small self-cleaving RNA enzymes, called twister ribozymes, in a ...
RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...
RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...
RNA molecules are an integral part of the human body: In cells, they ensure the transfer of genetic information and regulate the activity of genes. Some even act as catalysts, allowing chemical ...
The "RNA world" hypothesis proposes that the earliest life on Earth may have been based on RNA - a single-stranded molecule similar in many ways to DNA - like some modern viruses. This is because, ...
Atomic-resolution structure of a ribozyme yields insights into RNA catalysis and the origins of life
Santa Cruz, CA — Which came first, nucleic acids or proteins? This question is molecular biology’s version of the “chicken-or-the-egg” riddle. Genes made of nucleic acids (DNA or RNA) contain the ...
Ribozymes — catalytic RNA structures — require optimal salt compositions and concentrations to function correctly. Although several origin-of-life theories propose key roles for ribozymes in the ...
Researchers have visualized how a large RNA molecule assembles itself into a functional machine. RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like ...
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