Deep-learning model decodes the regulatory effects of DNA changes ...

Gene regulation is the process by which cells control the expression of their genes, determining when, where, and to what extent each gene is expressed. It is a fundamental mechanism that allows cells ...

For decades, biologists have known that the instructions for life are written in DNA, yet the vast majority of those letters seemed to sit in the dark, doing little that was obvious. Now a new ...

Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

Researchers at the School of Biological Sciences of The University of Hong Kong (HKU) have uncovered how eukaryotic cells can ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

Plant bioengineering—in which plant genes are modified to include desirable characteristics—is the key to solutions for problems concerning crop resilience and food security. Elements like gene ...

A team led by UC Davis poultry scientist Huaijun Zhou has created the first comprehensive map of gene regulation in breeds of chickens. The map could be a resource for finding resistance to H5N1 ...