DNA is often described as the instruction manual for building the fundamental components of life. Proteins are helpers that aid DNA in carrying out essential processes such as replication, repair, and ...

DNA, though tightly packed in the nucleus, is constantly threatened by damage from metabolism and external stressors. One particularly severe form of DNA damage is the so-called DNA–protein crosslinks ...

Proteins PIF1 and PCNA gather at sites of DNA damage in SETX-deficient cells, indicating activation of the BIR repair system. LA JOLLA, CA—The DNA inside our cells is constantly being damaged, and one ...

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...

As people age, their immune systems deteriorate. This makes them more susceptible to infections and can mean that vaccines ...

Researchers have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. Researchers from the University of Birmingham have uncovered ...

Researchers at the University of Bath have discovered how DNA damage caused by a faulty DNA protection and repair system can lead to neurodegenerative disorders such as Motor Neurone Disease (MND).

Researchers at The Institute of Cancer Research, London, have uncovered how the DNA repair enzyme XPF-ERCC1 is recruited to sites of damage and activated inside cells, resolving a long-standing ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...